Word: endostatin
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...endostatin, a compound discovered in Folkman's lab in 1997 by Michael O'Reilly, a researcher at the Dana-Farber Cancer Institute, has led the pack...
After a report on endostatin was published in the science journal Cell in January 1997, the protein's crystal structure was described in the fall of 1998 by Loeb Professor of Biochemistry and Biophysics Donald C. Wiley and associate Wuan-Hua Ding in the Department of Molecular and Cellular Biology. Clinical trials with human patients are slated to begin at Dana-Farber, Brigham and Women's Hospital, and Massachusetts General Hospital in just a few months...
...endostatin which brought Folkman to the front page of the New York Times...
...Folkman, who stresses he never used the word "cure"--"only the New York Times did." He also says his positive results in trials with mice did not seem to warrant the front page of the Times, since the so-called "third generation" drugs used in his research--angiostatin and endostatin--have yet to be tested in humans...
Still, since it takes an average of 15 years for experimental drugs to make it out of the lab and to patients, Folkman's endostatin is tantalizingly close to distribution...