Word: inhibitors
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...other so-called SSRIs have been a breakthrough on several levels. Compared with first-generation antidepressants, they are remarkably effective and relatively free of serious side effects. They work by slowing the brain's absorption of the mood-enhancing neurotransmitter serotonin (thus the term selective serotonin reuptake inhibitor...
There are, to be sure, some exceptions. A doctor might favor an ACE inhibitor over a diuretic, for example, when treating a diabetic patient with kidney disease, since ACE inhibitors help prevent renal failure. But all other things being equal, diuretics should be the first-line medical treatment--that is, if eating better and exercising more aren't enough to bring down your blood pressure on their...
...There was good news for patients struggling with drug-resistant AIDS; Roche's Enfuvirtide, or T-20, has had great success in two large late-stage trials. The drug is a so-called "fusion inhibitor," which, when added to a patient's larger drug cocktail, reduces the HIV levels found in the blood. T-20's trial performance was better than what researchers had hoped for. But even amidst this positive development, some AIDS experts expressed concern that the drug might have unknown long-term side effects. (The trials lasted just 24 weeks...
...OPTIONS Most treatments are aimed at relieving symptoms or prolonging life a few months or years. Surgery or radiation to remove or at least try to shrink any tumors. Chemotherapy. Herceptin for those cancers that express an excess of the Her2 receptor. Tamoxifen or an aromatase inhibitor, if they haven't already been used, for those tumors that respond to estrogen. (Clinical trials of both herceptin and aromatase inhibitors in earlier stages of breast cancer are under...
...signaling-inhibitor drug that he helped develop, is being studied as a potential treatment for colorectal and lung cancers as well as aids-related Kaposi's Sarcoma. Ullrich's U3 will attempt to identify more communication molecules that can be targeted in the war against cancer...