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...bacterium Escherichia coli. Now the genetically reprogrammed bug has the ability to produce something new. It begins cranking out the protein and, given the proper nourishment, making millions of carbon copies of itself, each capable of producing the same protein. Though each creates only a tiny amount, the cumulative output can be substantial. Biogen's accomplishment, brought off by Swiss Molecular Biologist Charles Weissmann and his international team of colleagues, was to re-engineer E. coli so that it would produce largely complete molecules of human leukocyte IF. At Harvard, Biochemist Tadatsugu Taniguchi, who first isolated an interferon gene while...

Author: /time Magazine | Title: The Big IF in Cancer | 3/31/1980 | See Source »

...gold mine, indeed. Most of the available IF is now obtained from the Finnish Red Cross and the Central Public Health Laboratory in Helsinki, which extract it from white blood cells separated from donated blood. The output in 1979 was minuscule, 400 mg (.014 oz.) gleaned from 45,000 liters (90,000 pints) of blood. The effort is so painstaking that, according to estimates by scientists at the California Institute of Technology, a pound of pure interferon would cost between $10 billion and $20 billion. That price will certainly decline as large companies enter the field with more efficient production...

Author: /time Magazine | Title: The Big IF in Cancer | 3/31/1980 | See Source »

...Journal's words, "trim the fingernails of the federal budget." But budget cuts deep enough to satisfy business would come at too high a human cost and would very likely bring a depression. A new direction is necessary: Carter should impose price controls immediately. Then the task of raising output by putting Americans back to work can begin. Programs to make the nation more energy-efficient are the best way in the long run to stop inflation, by improving productivity and lessening dependence on foreign oil. This entails efforts to revamp buildings, industry and transit which would employ many more...

Author: By Mark R. Anspach, | Title: Bondage and Discipline | 3/19/1980 | See Source »

...through the mid-1960s sales stayed consistently mediocre. Then the Federal Government began restricting the use of poisons for pest control around food. Emerson looked down from the heavens and smiled. A decade ago, the Kness Manufacturing Co. had four employees who with the owners managed a daily output of 60 traps. Now 28 workers turn out 2,500 mousetraps...

Author: /time Magazine | Title: In Iowa: The Mice Aren't Telling | 3/17/1980 | See Source »

...promising effort to expand its petrochemical production dramatically so that it could eventually become a major manufacturer and exporter of synthetics and resins. By 1985, if all goes well, China's production of ethylene will quadruple from 455,000 metric tons a year to 1.9 million. Polyethylene output is expected to expand from its very low current levels to about 1 million metric tons annually...

Author: /time Magazine | Title: Business: China Syndrome | 3/17/1980 | See Source »

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