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Word: nardil (lookup in dictionary) (lookup stats)
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...work in a similar way but probably on the neurotransmitters norepinephrine and dopamine. The tricyclic antidepressants (such as Elavil and Tofranil) also blocked the absorption of neurotransmitters, especially norepinephrine, but the drugs had significant side effects. Another class of first-generation drugs, the monoamine oxidase inhibitors (MAOIs) such as Nardil and Marplan, can be effective but can also produce dangerous side effects. A transdermal patch just approved by the Food and Drug Administration will give new life to MAOIs by reducing the side effects they sometimes caused when taken orally...

Author: /time Magazine | Title: Depression: What You Can Do | 1/20/2003 | See Source »

...Troppi, already the parents of seven, became apprehensive about the possibility of another pregnancy. Mrs. Troppi obtained a prescription for Norinyl, Syntex Laboratories' contraceptive pill, and her nervousness vanished. But her calm mood, she claimed, was the result of her druggist's mistake: he had given her Nardil, a tranquilizer, and Mrs. Troppi later gave birth to a son. If the Troppis can prove negligence, a Michigan court of appeals ruled, a lower court can then order the druggist to pay damages. In computing the amount, the appeals bench said, the value of the joys of parenthood...

Author: /time Magazine | Title: The Law: Decisions | 12/20/1971 | See Source »

...that in the brains of people suffering from severe depression, the enzyme monoamine oxidase breaks down too much of a group of mysterious brain chemicals called amines, in particular, one known as serotonin. The energizers (there are several on the prescription list, under such trade names as Marplan, Nardil, Niamid, Parnate) are supposed to block the enzyme and thus allow the serotonin to fulfill its normal function...

Author: /time Magazine | Title: Psychiatry: Injections for Depression | 5/7/1965 | See Source »

...those most widely used, four apparently work by a double-negative action, blocking an enzyme that breaks down brain-stimulating substances: isocarboxazid (Marplan), nialamide (Niamid), phenelzine (Nardil), and tranylcypromine (Parnate). Drugs with similar anti-depressant effects are imipramine (Tofranil) and amitriptyline (Elavil). All are prescription drugs, and should be taken only under close medical supervision...

Author: /time Magazine | Title: Awards: A Lift from Depression | 11/27/1964 | See Source »

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