Word: marplan
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...theory is that in the brains of people suffering from severe depression, the enzyme monoamine oxidase breaks down too much of a group of mysterious brain chemicals called amines, in particular, one known as serotonin. The energizers (there are several on the prescription list, under such trade names as Marplan, Nardil, Niamid, Parnate) are supposed to block the enzyme and thus allow the serotonin to fulfill its normal function...
...those most widely used, four apparently work by a double-negative action, blocking an enzyme that breaks down brain-stimulating substances: isocarboxazid (Marplan), nialamide (Niamid), phenelzine (Nardil), and tranylcypromine (Parnate). Drugs with similar anti-depressant effects are imipramine (Tofranil) and amitriptyline (Elavil). All are prescription drugs, and should be taken only under close medical supervision...
...effect on the underlying emotional state; all they can do is relieve the symptoms temporarily. Only since 1954 have there been tranquilizing drugs specifically designed and directed toward relieving signs of anxiety. For depression, psychiatrists are now prescribing the psychic energizers, of which half a dozen, such as Marplan and Niamid, have won fairly general acceptance. But talking it out in psychotherapy is generally recognized as the only measure that offers the possibility of a true cure. There is still controversy as to the value of different types of treatment, especially between the advocates of the analytic schools...