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...three new genes, known as clusterin, complement receptor 1 (CR1) and PICALM, were uncovered by two separate research groups, one in Wales and one in France, who linked the genes to the most common form of the memory disorder, late-onset Alzheimer's - the type that affects patients in their 60s or later and accounts for about 90% of all Alzheimer's cases. The only other gene connected with the condition, apolipoprotein E (ApoE), was identified in 1993; since, researchers have tirelessly hunted for other key genes, knowing that 60% to 80% of the progressive, incurable disease is genetically based...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

...discoveries mark a significant step forward in Alzheimer's research - until now, three of the four known genes associated with the disease were connected to the rarer, inherited form, which appears in adults as young as 40 or 50. The three additional genes, identified in the new papers, now tip the balance of genetic understanding in favor of the late onset condition that affects a majority of the 5.3 million patients living with the disease in the U.S. (See how to prevent illness...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

...came to a head this past week after Il Giornale published a series of articles alleging that Dino Boffo, editor of Avvenire, the Italian Bishops Conference daily newspaper, was a "homosexual known to the Italian secret services" and had paid damages to a woman in a 2004 harrassment case. Feltri wrote that he was publishing these accusations against Boffo, who had criticized Berlusconi's private life, as a response to his "moralistic campaign" against the Prime Minister. Il Giornale also hammered away at the Church for past scandals involving pedophile priests. After repeatedly and vehemently denying Feltri's charges, Boffo...

Author: /time Magazine | Title: An Offended Berlusconi Goes on the Offensive | 9/6/2009 | See Source »

...last three decades, successive Salvadoran governments have tried to curtail the two Maras. In the 1990s the Salvadoran government instituted a policy that became known as the Mano Duro (Strong Hand), that saw thousands of gang members jailed. But Mano Duro has not stopped the gangs. Corruption at the highest levels of government has allowed many leaders to go free or conduct business from behind bars. Saul Turcios Angel, also known as the "Pitbull," ran a kidnapping and extortion ring as part of Mara Salvatrucha. He escaped from a Salvadoran prison last year and was apprehended in Nicaragua earlier this...

Author: /time Magazine | Title: The Gangs of El Salvador: A Growing Industry | 9/6/2009 | See Source »

...personnel found Reddy's body deep in the jungles where his helicopter had crashed, the Congress party members in Andhra Pradesh banded together to press the party's central leadership to appoint his son, Y.S. Jaganmohan Reddy, in his place. YSR, as the late chief minister was popularly known, was a giant in regional politics and had run a tightly centralized administration with himself as the locus of authority. He had designated no clear successor. Now, most legislators in the state, being staunch loyalists, are now displaying that loyalty by rallying behind Reddy...

Author: /time Magazine | Title: In India: Will Merit Triumph Over Dynastic Ties? | 9/5/2009 | See Source »

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