Word: genese
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One immediate obstacle to translating the results to human cells involves the way that the scientists turned back time on the mouse skin cells. They used a retrovirus vector, piggybacking the genes for the growth factors and proteins onto this infectious ferry. Retroviruses, however, like HIV, can cause infectious diseases...
The other concern is perhaps more daunting-two of the four factors that can turn back the clock on adult cells so efficiently are known to cause cancer. One, in fact, was the first gene discovered to cause cancer in mice. "Figuring out how to reprogram cells without directly exposing...
But why should reverence for the state of nature—in our case, a collection of traits established by the unguided processes of evolution to suit small, hunter-gatherer societies—limit our progress today? Just because something is natural doesn’t make it more or...
Ali says he expects it will be at least a year - and probably longer -before any results of his trial are published. It can take months for the new genes to take effect. He is, however, "optimistic." He's not alone. "I don't have any doubt this is going...
Boatright and his colleagues are working on a technique that would let ophthalmologists fix genes that not just fail to express themselves, like Robert Johnson's, but that have mutated in a way that they express themselves abnormally, a trickier proposition because doctors need to add something and suppress something...