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The Harvard Institute for Proteomics (HIP) is working feverishly to develop a system called "The Wall," which will serve as warehouse for copies of all human genes.

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Hopes to Capitalize on Genome Draft | 6/30/2000 | See Source »

Ultimately, the Institute envisions a system from which scientists will be able to obtain copies of the genes they need to work with on demand, eliminating the time-consuming process of individually cloning genes as they are needed for specific research.

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Hopes to Capitalize on Genome Draft | 6/30/2000 | See Source »

This vision depends strongly on the development of "recombinational cloning" technologies that allow for genes to be cut and pasted out of the larger sequences of DNA. They will then be stored in the library in a uniform manner.

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Hopes to Capitalize on Genome Draft | 6/30/2000 | See Source »

This system would be flexible enough to allow researchers who want to express a protein in yeast, bacteria, insects, or any experimental system to use the stored genes easily.

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Hopes to Capitalize on Genome Draft | 6/30/2000 | See Source »

One major technology in development at the Center are DNA chips--matrices that contain a large set of genes from a particular organism all mounted on a silicon wafer.

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Hopes to Capitalize on Genome Draft | 6/30/2000 | See Source »

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