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...neuron to another. Prozac, Paxil, Zoloft and the other SSRIs slow the absorption of serotonin. Effective antidepressants that act on both serotonin and norepinephrine include Effexor and Remeron. Drugs like Wellbutrin work in a similar way but probably on the neurotransmitters norepinephrine and dopamine. The tricyclic antidepressants (such as Elavil and Tofranil) also blocked the absorption of neurotransmitters, especially norepinephrine, but the drugs had significant side effects. Another class of first-generation drugs, the monoamine oxidase inhibitors (MAOIs) such as Nardil and Marplan, can be effective but can also produce dangerous side effects. A transdermal patch just approved...

Author: /time Magazine | Title: Depression: What You Can Do | 1/20/2003 | See Source »

...into his problems." Father John Kiernan, who used to visit Solomon regularly, says he seemed unaware of the consequences of his rampage. But in 1999, Solomon carved an X across his chest, apparently with a fingernail, and last January he attempted suicide by swallowing 22 pills of the antidepressant Elavil that he had bought from another inmate...

Author: /time Magazine | Title: Voices From The Cell | 5/28/2001 | See Source »

...into his problems." Father John Kiernan, who used to visit Solomon regularly, says he seemed unaware of the consequences of his rampage. But in 1999, Solomon carved an X across his chest, apparently with a fingernail, and last January he attempted suicide by swallowing 22 pills of the antidepressant Elavil that he had bought from another inmate...

Author: /time Magazine | Title: Young Voices From The Cell | 5/20/2001 | See Source »

...against her. This kid will steal anything--a boyfriend, clothes, jewels--to get to the top. And don't bet against Sugar Town either. It's the kind of movie Robert Altman might make if he ODed on Elavil--a multicharacter comedy about the Los Angeles rock scene. Make that the trashed rock scene. For it's mostly about people who once had it, then lost it, but would like to find it again...

Author: /time Magazine | Title: Cinema: Rock Candy | 9/13/1999 | See Source »

...growing awareness of serotonin's central role in mood and emotion has been paralleled--and in some cases driven--by a boom in drugs that target serotonin more or less specifically. Among them are such popular antidepressants as Elavil, Prozac, Zoloft and the hot new herbal medication St. John's wort; powerful appetite suppressants including Redux and fenfluramine; and antipsychotics such as clozapine. Like every other drug, the ones that zero in on serotonin have side effects. Elavil makes people sleepy. Zoloft can trigger headache and nausea. Zoloft and Prozac may cause sexual dysfunction. All these symptoms are annoying...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

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