Word: zeneca
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...Monsanto Company, whose subsidiary Searle makes the wildly successful arthritis drug Celebrex, has been casting around for a merger partner for over a year, and now, executives say, the search is over. Monsanto will merge with Pharmacia & Upjohn, joining the ranks of other mega-merger firms like Astra-Zeneca and Rhone-Poulenc-Hoechst, to form a corporation worth about $52 billion. Why did it take so long for Monsanto to find its mate, and why was Pharmacia willing to take it on? The answers lie in Monsanto's agri-chemical division, a successful but controversial arm of the company, which...
...formatted on a regular 3 1/2-in. floppy disc (available for Windows or Mac), free at cancertrials.nci.nih.gov or by calling 800-4-CANCER. You'll probably have to wait a few weeks to receive it, since the NCI has already mailed out most of the copies it had on hand. Zeneca Pharmaceuticals, which manufactures tamoxifen under the brand name Nolvadex, also plans to distribute the disc...
...cells, including about 90% of lung-cancer tumors, some prostate tumors and other malignancies. Researchers at M.D. Anderson Cancer Center in Houston are testing an antibody to EGF receptors in patients with advanced head and neck cancers. But most other groups, including teams at drug makers Pfizer, Novartis and Zeneca, are using smaller molecules that, unlike antibodies, could ultimately be taken orally. "We have a very exciting tablet that is taken once a day," says Dr. George Blackledge, head of new cancer projects at the Zeneca Group. Testing on patients is still at a very early stage. "We have...
...YORK CITY: News that British pharmaceutical firm Zeneca P.L.C. has taken control of the management of 11 cancer clinics it owns in the U.S. raised a host of ethical questions about whether a drug manufacturer should also oversee a patient's care. No drug manufacturer has ever directly overseen the full range of a clinic?s patient care. While government regulators may allow a relatively small fish like Zeneca to get away with such an arrangement, TIME's Dan Kadlec says they will probably crack down if the industry's heavyweights try to follow suit. "If it gets too cozy...
CHICAGO: The ethics of the Zeneca case looked even more problematic following news that the maker of a pricey synthetic thyroid hormone suppressed research findings that cheaper alternatives are just as effective in controlling thyroid-related illnesses. A story in Wednesday's issue of the Journal of the American Medical Association said the Knoll Pharmaceutical Company attempted to discredit and keep from public view a University of California study that found Synthroid, the firm's flagship thyroid medication, no more effective than the generic competition. Although Synthroid's prior manufacturer, Flint Laboratories, commissioned the study, Knoll reportedly threatened author Betty...