Word: untoward
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Dates: during 1930-1939
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Charlie Pommer's 68 years, high brow, jutting nose, pince-nez and white-piped vests make him the picture of statesmanship, but not the mouthpiece. Last week some newsmen feared a Democratic victory in Philadelphia might remove Mr. Pommer from his post and their ken. Against that untoward hap, they set about collecting his legendary sayings...
...puerperal fever victims. He tried the vaccine out on hundreds of mice, then on a large group of nonpregnant women, to make sure it was not dangerous. "Aside from an occasional complaint such as slight soreness at the site of injection, or mild malaise," said the doctors, "no untoward reactions were observed. Several women volunteered the information that they . . . felt better following the vaccinations...
Toxicity. "Untoward reactions, even death, may result from the administration of sulfanilamide. . . . The toxic effects are more commonly the results of its indiscriminate use, but may occur from an idiosyncrasy. . . . Fifteen per cent of patients cannot take large doses, and 10% are unable to tolerate it at all. Patients in bed tolerate larger doses than do those who are ambulatory. Patients exposed to sunlight are more apt than are others to develop a skin rash." The rash may resemble measles, scarlet fever or hives, and break out on the face, trunk or extremities. Slight poisoning by sulfanilamide causes headache, vomiting...
...Untoward Effects...
...Journal further states, "In view of its untoward and disturbing circumstances, it must be stated that benzedrine sulfate can be more safely prescribed when the patient is under close observation in the hospital. Its use in outpatient practice should be undertaken with considerable caution and only under favorable circumstances...