Word: tumorous
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Dates: during 2000-2000
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...were pleased that the PRS 400, our miniature X-ray source, was included in your Inventions 2000 report, but we want to clarify one point for your readers. Our device is a valuable tool for radiation treatment given in the operating room at the time of tumor removal and for the treatment of brain tumors for which radiation is used instead of surgery. At the present time, it is not a replacement for standard radiation therapy or chemotherapy. Clinical trials are under way, however, that could prove that treatment during surgery using our device may be the only therapy needed...
...first and most famous of these are Wyeth-Ayerst’s Enbrel, and Remicade, manufactured by a subsidiary of Johnson and Johnson, which have been in use now for roughly two years. Both Enbrel and Remicade inhibit a key messenger in the inflammatory cascade known as the tumor necrosis factor (TNF). The drugs are both more effective than traditional medications, and more likely to slow down joint degradation. "The idea that biologics could prove effective against autoimmune diseases has been firmly established by the TNF story," says Dr. H. Michael Belmont of the Hospital for Joint Diseases in New York...
Other antibodies carry tiny payloads of radioactive isotopes or poisons, which kill the tumor cell without affecting surrounding tissue. IDEC Pharmaceuticals, in San Diego, just completed final rounds of testing Zevalin, an antibody that is hooked to the radioactive isotope, yttrium-90. Last month, IDEC reported that the tumors in about one third of 73 late-stage non-Hodgkins lymphoma patients were undetectable after being treated with Zevalin...
...drug, which can be taken as a pill, has at least one advantage over other cancer treatments. Most traditional cancer treatments--such as surgery, chemotherapy and radiation--try to kill tumor cells directly, but 2ME2 also prevents angiogenesis, the growth of new cancerous blood vessels in the body...
Folkman's laboratory at Children's Hospital has also developed Angiostatin and thalidomide--two drugs other than 2ME2 and Endostatin that also disrupt blood flow to tumor cells...