Word: testing
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Plenty of movies get tweaked after test screenings, but Snakes on a Plane, out Aug. 18, may be the first to be changed by audience response before the audience saw it. "Personally, I think it's great," says Jackson. "They saved the movie." When the actor first signed on, he and Ellis agreed that people who like the title are probably not easily offended. But when Jackson arrived for shooting, the script had been neutered to garner a PG-13 rating. "They restricted my cursing and restricted the gore," he says. "It was kind of a waste of time...
...against this gloomy backdrop that Kiernan and a fellow neurologist from Sydney's Prince of Wales Medical Research Institute last week announced a breakthrough. Among the many gaps in the MND puzzle has been a definitive test: clinicians are able to diagnose the condition only after months of observing symptoms and excluding other disorders. Kiernan, an associate professor at the University of New South Wales, and Ph.D. student Steve Vucic say they've developed a better way. Described in the American journal Muscle & Nerve, it involves 40-year-old technology called transcranial magnetic stimulation, which the pair have tailored...
...Kiernan and Vucic observed that this twitch, as registered on their computer screen, was more pronounced in 28 MND patients than in people free of the disease; even a smaller current produced similar results. "The difference was stark," says Kiernan. "Almost as soon as we'd start the test, Steve and I would know (if the patient...
...test is painless and takes about 30 minutes. But the absence of an effective treatment for MND - of which there are some 1,400 sufferers in Australia - raises the question of whether there's much to be gained from early diagnosis. Kiernan and Vucic are adamant that there is. Their procedure can detect the disease in its very early stages, they believe, when symptoms amount to no more than stiffness, weakness or cramping in the hands - up to a year before a clinician relying on traditional methods could hope to make a diagnosis. Starting patients earlier on riluzole, which works...
...that precluded offering greater power to the Sunnis in the hope of drawing them in, unwilling to rein in the militias associated with his own sect, and (in the case of the Kurds) hostile to a federalism that would allow the creation of de facto-independent regions. One early test will come over the next month as Maliki cobbles together a cabinet - Jaafari had favored putting members of the Shi'ite alliance in charge of the defense and security portfolios that Washington wants to see controlled by U.S.-friendly secular leaders...