Word: ribavirin
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Dates: during 1980-1989
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There has also been little progress in developing AIDS drugs that interfere with viral reproduction. The only drug approved by the FDA is azidothymidine, or AZT. An experimental drug, ribavirin, made by ICN Pharmaceuticals of Costa Mesa, Calif., seems to be less effective than had been claimed. Dr. Andrew , Vernon, a member of a study group at Johns Hopkins University, reported that in a 28-week experiment, 217 male pre-AIDS patients who took ribavirin showed no significant benefits...
...fastest-selling pharmaceuticals in border towns now is Ribavirin, a drug developed in the U.S. to treat AIDS but not approved by the Food and Drug Administration. Despite official doubts about Ribavirin's efficacy, thousands of Americans are crossing the border to buy it; smuggling rings have been formed to transport large quantities to the U.S. for resale. "I have had people come in saying they will buy all I can get," says a pharmacist in Ciudad Juarez...
...French announcement and the resulting furor underscore the frenetic pace of AIDS research. At the NIH in Bethesda, Md., calls come in virtually every day from drug manufacturers claiming to have a new treatment for the disease. About half a dozen drugs are currently under serious study. Several, including ribavirin, suramin and one called compound S, have shown promise in blocking the replication of the AIDS virus. But few, if any, have demonstrated the potential to rebuild the devastated immune systems of AIDS patients...
...similar claim is made on behalf of ribavirin, a drug already marketed in 30 foreign countries by Viratek, a small West Coast firm. Ribavirin is said to interfere with the virus' reproduction by blocking protein synthesis in affected cells. Another drug sold abroad but not in the U.S. is Newport Pharmaceuticals' isoprinosine. According to Newport President Alvin Glasky, the drug "speeds up the body's natural curing process" by boosting the immune system. But so far, experts at NIH reject it as being of no proven benefit. Last week scientists at the University of Texas Health Science Center...