Word: pravachol
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...first glance, you might think that the study released last week comparing the cholesterol-lowering drugs Lipitor and Pravachol--funded by Pravachol's maker--produced a surprise slam-dunk for Lipitor. After all, the trial of more than 4,000 patients showed that those who started taking Lipitor instead of Pravachol within a week or so after being hospitalized for a heart attack or unstable angina had a 16% lower rate of getting worse--dying, suffering a subsequent heart attack or stroke, or requiring bypass surgery. But the seemingly obvious conclusion is not necessarily the right one. Here...
...level has always been a bit elevated (it hovers around 100, which is right at the limit recommended by the U.S. government). So I followed with particular interest the results of the first head-to-head comparison of two of the most popular statins: Lipitor (made by Pfizer) and Pravachol (Bristol-Myers Squibb...
...have heard (and if you haven't, Pfizer's marketing department will make sure you soon do), the face-off was a big win for Lipitor. In an 18-month study of 502 patients with average LDLs of 150, Lipitor not only lowered those levels more than Pravachol did (to 79 vs. 110), but it also had a measurable effect on the buildup of plaque in patients' arteries. Pravachol merely slowed the progression of those fatty deposits, whereas Lipitor stopped them cold--and may have even shrunk them...
...marketed. At Merck in the early 1990s, her name became legend when she took charge of a struggling ulcer remedy called Prilosec and transformed it into a worldwide best seller. At Bristol-Myers Squibb in the late '90s, she worked the same magic on billion-dollar brands like Pravachol (for high cholesterol) and Glucophage (for diabetes). Today Potter, 44, is the COO of the world's No. 2 biotech firm, Genentech, where she's working to bring 20 drugs to market over the next decade. By then, observers believe, Potter stands a good chance of becoming...
ADDED VALUE Are you on statin drugs to lower your cholesterol? Here are benefits you probably never counted on. A Scottish study shows that Pravachol, one brand of statin, reduces the risk of developing diabetes 30%. And a study of heart-attack survivors finds that Pravachol reduces the odds of stroke 20%. No, it's not time to add statins to the drinking water. They need to be taken every day for life, and they carry risks--including liver damage...