Word: plasminogen
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...larger research project into hospitals’ performance in quality improvement campaigns for stroke patients, including the American Stroke Association-based “Get With the Guidelines.” It will appear in the November issue of the journal Stroke. The drug in question, tissue plasminogen activator (tPA), is the only clot-dissolving drug approved in the treatment of strokes and can only be used within three hours after symptom onset, according to Eric E. Smith, lead author of the study and assistant neurologist at MGH Stroke Service. Some doctors avoid using tPA at early stages of stroke...
...large drug company, left to become president of Genentech. To prepare for the introduction of Protropin, Raab helped build a national marketing organization, which includes 15 hospital-based sales representatives with an average of 15 years' experience. Now Raab is working on plans to sell interferon and TPA (tissue plasminogen activator), a drug that dissolves blood clots and thus may help prevent heart attacks...
...study, titled “Antiactin Targeted Immunoliposomes Ameliorate Tissue Plasminogen Activator-Induced Hemorrhage After Focal Embolic Stroke,” researchers from the Harvard Medical School (HMS) outline a method that will potentially increase the success of ischemic stroke treatment...
Currently, the only FDA-approved drug for ischemic stroke victims is tissue plasminogen activator (tPA), which is also given to patients who have suffered a heart attack...
...patient fares after a stroke depends on several factors, including how much of the brain has been affected; how soon and what sort of treatment is started (clot busters like TPA, or tissue plasminogen activator, should be administered within three hours for ischemic strokes but not for hemorrhagic strokes, lest they cause even more bleeding); how severe the symptoms are (paralysis is worse than simple weakness); and the patient's general health before the brain injury...