Word: placebos
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...evidence he's been waiting for. In a paper published in February in the journal Circulation, researchers analyzed data on women who took part in the Jupiter trial, a large, industry-funded study that sought to compare the effectiveness of the statin Crestor (rosuvastatin) with that of a placebo in healthy patients. The study, which ended in 2008, involved nearly 18,000 participants - including 6,801 women, more than in any previous statin trial - who had high levels of C-reactive protein, a risk factor for heart disease, but did not have high cholesterol...
...gender-specific analysis showed that women who took 20 mg of Crestor daily for an average of 1.9 years had a 46% reduction in cardiovascular events - similar to the 42% reduction in men - compared with the placebo group. "I said once we had the large numbers of women, we'd see benefit. Jupiter now provides that evidence," says Grundy...
Meanwhile, women on Crestor were more likely to develop diabetes compared with those getting a placebo - a result not seen in men. And because the trial lasted only 1.9 years on average, researchers say the full magnitude of the side effects may not have been captured...
...European Commission will unveil a 10-year plan outlining the first tentative steps toward forming a common economic policy. The "Europe 2020" strategy is being touted as a way to boost competitiveness and growth over the next decade. Skeptics, however, warn that it is no better than a placebo for the curmudgeon European patient...
...argument I've heard is that it would be unethical to compare vaccines against a placebo because you would be withholding crucial treatment from patients. Do you agree? No. We don't know these vaccines work, so you can't make that claim. But if you really find placebos to be unethical, then why don't you randomize against masks, hand-washing, gloves, distancing - public health measures that have proven to be effective...