Word: malariae
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...program: "They are coming here less than ill clothed, less than ill fed and without homes. We have had to start from scratch." In fact, some arrived at Ben Gurion International Airport carrying nothing but water pails, cherished possessions in drought-stricken Sudan and Ethiopia. Many suffer from malnutrition, malaria, tuberculosis, jaundice, typhus and tapeworm. "I had to go back to my textbooks to look up some of these diseases," said an Israeli doctor...
...cell in the culture is an identical descendant, or clone, of the original hybrid, the antibody is pure and therefore a precise instrument. Says Milstein: "It al lows you to discriminate one molecule from another." Monoclonal antibodies can home in on targets ranging from a malignant cell to a malaria parasite to a specific structure in the brain. They have already showed promise in treating transplant and cancer patients...
...being developed by Dr. Richard Carter at NIH, but much work remains to be done. An experimental vaccine for all three stages may be only a decade away, according to Pathologist Sydney Cohen of Guy's Hospital medical school in London. "If it is very effective," he says, "malaria eventually will be eradicated like smallpox...
...history holds one lesson for the malariologist, it is modesty in the face of nature. Scientists admit that vaccines alone will not defeat this resilient organism. "Controlling malaria will take all the resources we have: insecticides and drugs, as well as vaccines," says Top. Drug research is continuing at Walter Reed and elsewhere. Mefloquine, discovered by the Army in 1974, remains about 98% effective against the deadly falciparum strain, but signs of resistance are already appearing. Quinghaosu, a Chinese drug derived from the wormwood plant, is "extremely promising," according to Lucas of WHO. But because drug resistance develops quickly...
...University of California, Riverside, may have found a way of solving these two problems by spraying breeding grounds with a naturally occurring bacterium that kills mosquito larvae. But the method is costly, and Federici asks, "Who is going to pay for it?" That is the ultimate question in controlling malaria. According to one estimate, the cost of producing a malaria vaccine and distributing it to Third World children would be $200 million. In countries where less than $5 per capita is spent on annual health care, even a mosquito net is a luxury. -By Claudia Wallis. Reported by Mary Carpenter/New...