Word: falciparum
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...landmine-ridden territory. Soon, however, they could be the ones to put millions of others at risk. On the Thai-Cambodian border, a rogue strain of malaria has started to resist artemisinin, the only remaining effective drug in the world's arsenal against malaria's most deadly strain, Plasmodium falciparum. For six decades, malaria drugs like chloroquine and mefloquine have fallen impotent in this Southeast Asian border area, allowing stronger strains to spread to Burma, India and Africa. But this time there's no new wonder drug waiting in the wings. "It would be unspeakably dire if resistance formed...
...genetic map that could serve as an “early warning system” for detecting drug resistance in a malaria-causing parasite. The results of the study, released Sunday in the advance online edition of the journal Nature Genetics, may help in the fight against Plasmodium falciparum, the most deadly of the four parasites responsible for human malaria. The lead researcher, Dyann F. Wirth, who is also chair of the School of Public Health’s Department of Immunology and Infectious Diseases, said that the finding could help producers of malaria vaccines respond to adaptations...
...better understand why malaria has become such a threat and what can be done to stop the disease, it helps to know a little biology. Malaria is caused by four closely related parasites, the deadliest of which is Plasmodium falciparum, which has a particular fondness for anopheles mosquitoes. The parasites enter the bloodstream when an infected mosquito bites a human. Then they multiply inside the host's liver and red blood cells. (That's why pregnant women, who make lots of blood to nourish their growing fetus, are especially vulnerable.) Eventually the red blood cells burst with a new generation...
...falciparum causes the most lethal form of human malaria, which is the world's most serious parasitic tropical illness, killing 1 million to 3 million people each year...
...genome sequencing of Plasmodium falciparum and the initial lessons that scientists have learned about the parasite are outlined in two new journal articles by Dyann F. Wirth, director of the Harvard Malaria Initiative and professor of immunology and infectious diseases at HSPH...