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...pill of synthetic mescaline available in some corners of the underground, which, during its first four hours, gives you a gush of pure, unexplained happiness. And the same goes for tense, moral anguish. Perfectly above-ground psychiatrists have been giving their uncomfortably anxious patients a drug called librium (itself one of the atomic elements) to space them out a little more...

Author: By John G. Short, | Title: Outline for the Coming Chemical Society, Or Dexedrine vs the Old Academic Process | 5/9/1969 | See Source »

...Jack Miller noted that the widely used "major tranquilizer," chlorpromazine (Thorazine), has been shown to produce breaks in a few cases, and even the antihistamine diphenhydramine (Benadryl) in one case. Western Reserve's Dr. Mor ton Stenchever added the popular minor tranquilizers chlordiazepoxide and diazepam (Librium and Valium) to the list as causing breaks in animal cells, though this effect has not yet been confirmed in human patients. The antibiotics have not been shown to cause breaks, except for two compounds used only for advanced cancer. But the heart stimulant digitoxin causes breaks, said Buffalo's Dr. Maimon...

Author: /time Magazine | Title: Genetics: Drugs & Chromosomes | 9/15/1967 | See Source »

...agonies of withdrawal. They have since discovered that there are lots of non-narcotic drugs that can lead to addiction and similar withdrawal sickness as well. Long-term use of barbiturates will do it. So will the so-called "minor tranquilizers" like meprobamate (Miltown or Equanil) and chlordiazepoxide (Librium), and the stimulant amphetamines ("bennies" or "goofballs"). Last week the U.S. Food and Drug Administration's Medical Director Joseph Sadusk told the A.M.A. that non-narcotic drug habituation has grown so widely that it has become a big business in the U.S. and has attracted the rapacity of vice...

Author: /time Magazine | Title: Drugs: The Non-Narcotic Addicts | 7/2/1965 | See Source »

...fact was that Librium, like all powerful drugs from digitalis to cortisone, can indeed be dangerous unless given in carefully controlled doses, with the patient under close watch. Before a psychiatrists' round table a fortnight ago, Dr. Murray conceded that he had been dosing his office patients heavily, sometimes with 75 milligrams a day. Said Round-Table Chairman Anthony Sainz, research chief of New York's Marcy State Hospital: "All of us who heard Dr. Murray thought the side effects were the result of giving too high a dose and lack of control in administering it. The recommended...

Author: /time Magazine | Title: Medicine: Report on Librium | 5/30/1960 | See Source »

Most psychiatrists expect some undesirable, incidental effects from Librium but not so many or so bizarre as those reported by Dr. Murray. They agree that with the right dosage and for the right type of patient, Librium is a useful drug...

Author: /time Magazine | Title: Medicine: Report on Librium | 5/30/1960 | See Source »

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