Word: kligman
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...Israeli bombs but Palestinian terrorists. The article explained in detail everything the Israelis have destroyed and how miserable Palestinians' lives are as a result. Not once did it explain the defensive reasons for Israel's actions. The blame lies solely with the Palestinians for encouraging terrorist activities. Aaron Kligman Montreal Ruining Our Pun Re "A not-quite-immaculate conception" [Oct. 16]: The tongue-in-cheek headline for the report on actress Keisha Castle-Hughes' pregnancy confused the Immaculate Conception of Mary with the virgin birth of Jesus. Roman Catholic dogma teaches that Mary was conceived without original sin and therefore...
...AARON KLIGMAN...
...prescription medication for acne. Older patients began reporting an unexpected benefit: not only did their pimples disappear, but fine age lines, freckles and blotches faded or vanished as well. What is more, their skin took on a rosy, youthful glow. The drug's developer, Dermatologist Albert Kligman of the University of Pennsylvania, was at first skeptical of the claims. But about a decade ago, he began studies to determine the effects of Retin-A on sun-damaged skin. With a team of researchers, Kligman took skin biopsies and examined the tissue microscopically. "To our surprise, there were changes that were...
Intrigued by Kligman's early results, the drug's manufacturer, Ortho Pharmaceutical Corp. of Raritan, N.J., began sponsoring clinical trials around the country. One method used to assess the drug: researchers make molds of facial skin with dental modeling plastic, then scrutinize the impressions with an imaging analyzer of the kind used by NASA to examine the moon's surface. The company claims that results so far have been positive and plans to submit its findings next year to the Food and Drug Administration. Although it is already approved for treating acne, Retin-A cannot be promoted as an anti...
...fountain of youth either, doctors agree. "It doesn't make old people into young," warns Kligman. "It does not help very deep wrinkles. It does not help sags or bags or very loose skin. People who need a face-lift are not going to get any benefit." Dermatologist Jerome Shupack of New York University School of Medicine puts it more bluntly: "Retin-A won't do much for a prune." Indeed, some physicians wonder about the popularity of the drug at all. "The only thing I see Retin-A doing is irritating the skin and increasing the susceptibility...