Word: hilleman
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Dates: during 1950-1959
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...allergist in Philadelphia raised the possibility that greatly reduced vaccine doses can supply adequate protection if injected into the skin instead of under it. Writing in Philadelphia Medicine, Dr. Louis Tuft of Temple University reports that, on the basis of limited experiments by Walter Reed's Dr. Maurice Hilleman, one-tenth the present dose given intracutaneously produces approximately the same antibody response as the present recommended dose given subcutaneously. Suggested reason: vaccine injected into the skin is absorbed more slowly, and cells have more time to respond...