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Word: helpers (lookup in dictionary) (lookup stats)
Dates: during 2000-2000
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Usage:

...things may be looking up, thanks to advances in molecular immunology that have spurred the creation of new generation of drugs. It is becoming clear that a cell called CD4+, or helper T cell, is a central player in both the healthy and the pathological immune response. "The activation of the T cell-like the branches of government-is controlled by a series of checks and balances," explains Dr. C. Garrison Fathman, a clinical immunologist at Stanford University...

Author: /time Magazine | Title: Immune System Disorders | 12/18/2000 | See Source »

...cell’s dependence on another cellular player: the antigen presenting cell. The APC is an omnivorous creature whose job, among other things, is to gobble up microbial invaders. To initiate the immune response, the APC coughs up a molecule from the bug it has eaten, latches onto a helper T cell and "presents" it with the target molecule, instructing the T cell to prepare its troops for war. This activation is tightly controlled. It cannot occur without the lock-step interaction of a several proteins on the surface of both cells-one of which is known...

Author: /time Magazine | Title: Immune System Disorders | 12/18/2000 | See Source »

That story, in fact, has inspired trials of nearly two dozen new biotech medicines. IDEC Pharmaceuticals in San Diego, Calif., for example, has zeroed in on the interactions between helper T cells and APCs to develop antibody drugs against lupus and RA. Their anti-RA antibody selectively switches off T cells involved in autoimmune responses by binding the CD4 molecule on their surfaces. Amgen, of Thousand Oaks, Calif., has developed a drug that works by blocking Interleukin-1, another molecule that promotes inflammation...

Author: /time Magazine | Title: Immune System Disorders | 12/18/2000 | See Source »

H.W.F.M.C.O.T.I: "You are a HELPER WHO FINDS MISSING CHILDREN OVER THE INTERNET...Behind your reserved exterior lies a dedicated person who in his heart of hearts wants to help missing children. God bless...

Author: By Soman S. Chainani, CRIMSON STAFF WRITER | Title: Soman's In the (K)now: A Pop Culture Compendium | 9/22/2000 | See Source »

...along with the decoy balloon and launch container. From here on out--in the final 100 seconds--the interceptor will be on its own, getting no guidance from the ground. But it will still be getting help. At this point, the balloon, the designated hindrance, will become the sly helper...

Author: /time Magazine | Title: Missile Impossible? | 7/10/2000 | See Source »

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