Word: grifo
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Dates: during 1990-1999
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...sounds almost as if it came from science fiction. Researchers know that older women's eggs are less fertile than those of younger women, and suspect that the fault lies not in the chromosomes but in the biological machinery that controls cell division. To test this idea, Dr. Jamie Grifo, director of reproductive endocrinology at New York University Medical Center, and his colleague, Dr. John Zhang, have microsurgically transplanted the chromosome-containing nuclei from older women's eggs into younger women's eggs from which the nuclei have been removed. The transplants took, and while 40% to 50% of older...
...Grifo's eggs have not yet resulted in any births, but an upside-down version of the procedure has succeeded. At the St. Barnabas Medical Center in Livingston, N.J., Drs. Richard Scott and Jacques Cohen have been taking cytoplasm--the nonnuclear part of a cell--out of young women's eggs and injecting it into the eggs of older women. One egg with refurbished cyotoplasm has grown into babyhood; another birth is expected next spring...