Word: geneses
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The scientists hope to learn how T-box genes turn on and off. That could give them clues to human birth disorders like Holt-Oram syndrome, which is characterized by stunted arms and hands and is linked to these genes. As for the chicks, the scientists didn't let them...
The work, described in last week's Nature, centers on so-called T-box genes. Common to all vertebrates, including humans, they're important in the development of limbs in the embryo--determining, for example, whether they become hind- or forelimbs (or in chickens, legs or wings). But, says geneticist...
To unravel the puzzle, the scientists infected the unformed wing region of day-old chicken embryos with a virus carrying a T-box gene known as Tbx-4. A day later, they transferred the tissue to other embryos still in their shells. The transplanted cells quickly grew into recognizable legs...
While the results are tantalizing, Gorman cautions that they are far from conclusive, and years away from being proved safe and effective for human application. "Mouse models," she says, "don?t always work in humans." Moreover, tinkering with genes poses special problems. "We don?t know what the consequences are...
Serbian ethnic cleansers can draw on long evolutionary memory for tribal hatred: by now it must seem that hate, like other tribal features, is carried in the genes. Suburban tribes have to hone enmities on the spot, so they require immediate inducements. The killers must be perceived as weak and...