Word: genese
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GeneFormatics of San Diego, for instance, uses bioinformatic algorithms to help drug companies predict the function of proteins encoded by newly discovered genes. It does this by comparing the new proteins with those of known structure, generating a "fuzzy" picture of what each looks like. That, in turn, suggests what...
But that's about to change. With the mapping of the genome--the twisted double strand of DNA that carries the instructions for making every cell in the human body--the process by which new drugs are developed is being turned upside down. Trial and error, which is how medicines...
Buoyed by the success of these trials, researchers are busy investigating other compounds that would interrupt HIV's reproductive cycle at critical points. One particularly attractive target: a molecule that could prevent HIV from inserting its genes into its host's genome. That would give doctors two new ways to...
For this reason, people whose advancing years place them at high risk for Alzheimer's disease would be wise to place their hopes not in any particular treatment strategy but in the broad range of options that the genetic toolbox is so rapidly opening up. Right now, it is encouraging...
Gamma secretase emerged as an attractive target shortly after 1995, when scientists working with DNA donated by families prone to early-onset Alzheimer's disease finally succeeded in cloning two genes known as presenilin 1 and presenilin 2. In a series of experiments, researchers established that these genes exercised tight...