Word: fats
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What sort of message should an anti-obesity campaign send, given that diet experts are still wrangling over such issues as whether low-fat or low-carb diets work better? "How about just eat less, move more and eat your fruits and vegetables?" suggests Nestle. Few people appreciate more fully than she just how difficult it would be for the Federal Government to approve such a message. "Move more" is not a problem. The Centers for Disease Control and Prevention (CDC) has budgeted $193 million for its Verb campaign, encouraging young Americans to be active. "Eat less" is another matter...
...year, up from 20,000 in the 1970s, according to a report by the Henry J. Kaiser Family Foundation. Up to 70% of those ads are for food (though some researchers put the figure much lower, at a still considerable 25%). Ads for high-fat, high-salt foods have more than doubled since the 1980s, while commercials for fruits and vegetables remain in short supply...
Doctors used to joke that the best way to combat obesity was to build up your biceps ... in order to push yourself away from the table. Then came the discovery in 1995 of genes that regulate leptin, the hormone that controls how much fat your body stores. Since then, scientists have identified dozens of compounds related to weight, some released in the brain and others...
...supposed to tell the body when to eat and how much, and the myriad signals that originate in the gut and then flow into the brain, triggered by the amount of food you eat. These messages order the body to burn calories right away or store them as fat for later...
Scientists at Regeneron, based in New York, are tapping into the same feeding hub in the brain but through a different protein that is more closely related to leptin. Regeneron's agent, Axokine, fools the brain into thinking that the body's fat stores are well stocked, short-circuiting the need to eat. People who took Axokine and stayed on a low-calorie diet and exercise program lost twice as much weight as those who relied on diet and exercise alone...