Word: evening
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Dates: during 2000-2000
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...Even some admirers say Boies can be less than straightforward during settlement negotiations, and many complain that he's maddeningly, even irresponsibly hard to reach because of his tendency to do 17 things at once. His partner Robert Silver acknowledges that "life might be easier" if Boies did only 13 things at once. "But," Silver adds, "you wouldn't want to tinker with the psychology" that makes him eager to do 17 things in the first place...
Comparing the human genome with those of other organisms, from bacteria to insects to mammals, will help biologists understand how more complex species evolved from simpler ones--and even pinpoint the precise bits of genetic information that are uniquely human. "It has to be a milestone in human history when you have a first look at your instruction book," says James Watson, who with Francis Crick discovered the structure of DNA a half-century ago. "Having this book will change the world...
...where he began trying to locate and decode a gene that governs production of a brain-cell protein. The work was agonizingly slow, and when he heard about a computerized machine that used lasers to automatically identify the chemical letters in DNA, he went out and bought a prototype--even though his NIH bosses wouldn...
Eventually, even his bitterest critics had to face the fact that Venter had not been dealing in hype. And, in the end, the genome project was forced to adopt some of Venter's ideas to avoid being left behind. "It was," admits Watson, "the correct way to go." Thanks to Venter's maverick ways, says Phillip Sharp, director of the McGovern Institute for Brain Research at the Massachusetts Institute of Technology, "we have the human genome four years early, and it's spectacular. Craig is to be applauded for doing this...
...genome seems to carry amazingly detailed evidence of our evolutionary history, including traces of viruses that long ago invaded our DNA and became a permanent part of us. Says Smith: "We hope over the years to get a clear picture of how our genome was put together and even see where it might be going." Not just how, but when. For example, the genome evidently contains a molecular clock in the form of sequences of letters that are repeated between the genes and have mutated over time. The rate of these changes could serve to time-stamp specific traits...