Word: complexity
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Dates: during 2000-2000
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...pinpointing the genetic basis for disease and an individual's genetic response to medication is only a small part of what genomics is about. Further along the biochemical cascade of cause and effect are the proteins, the ultimate products of genetic information. Understanding the nature of proteins and their complex interactions will give scientists an entirely different and perhaps even more valuable insight into disease--and again, nobody's waiting for the genome sequence to be done to start finding out. (See accompanying story...
Maybe too much of an increase, argues Tom Delbanco, chair of general medicine at Harvard Medical School. "Discovery is intoxicating," he says. "But the consequences of discovery are often complex, and instead of progress, it can lead to disaster." Delbanco is worried that the revolution in genetic medicine may further drain the limited amount of time that physicians have to spend with patients and add even more costs to the already expensive health-care system...
Although proteins are the direct result of the instructions coded in our DNA, they are far more variegated and complex than DNA. They have to be. Every chemical reaction essential to life depends in one way or another on their services. Proteins are the beams and rafters of the cell and the glue that binds the body together; they're the hormones that course through our veins and the guided missiles that target infections; they're the enzymes that build up and break down our energy reserves and the circuits that power movement and thought...
Closely linked to this research is the Center for Genomics Research (CGR), which is building a new home in the Cabot Science complex in Cambridge...
...development area, it has to be regarded as extremely difficult," Grogan said. "It's going to be complex...