Word: chemo
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Dates: during 1990-1999
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...Baby Bills," similar to the Baby Bells spawned by the court-ordered breakup of AT&T. Each of these mini-Microsofts would be nearly identical, selling the same software but in competition with one another. George Washington University law professor Bill Kovacic, an antitrust expert, calls this a "radical chemo-therapy" option. Notwithstanding the AT&T and Standard Oil cases, he says, judges are often reluctant to go this far in restructuring an errant monopolist...
George's wife Connie and the rest of the family are trying to get him to slow down, but he doesn't listen. He beat cancer a few years back and slowed up during the chemo, but he wouldn't quit. In downtown New Castle, the FIREWORKS CAPITAL banners fly because...
Bradfield's doctor put her in touch with UCLA's Slamon, who was testing a brand-new antibody that targeted the HER-2/neu protein. Although Slamon was using the antibody in combination with chemotherapy--and Bradfield was loath to go back to chemo--the combined therapy proved miraculous in her case. Sixteen small tumors in her lungs melted away. By 1993 she was in remission, and still is. "I got to be at my son's wedding," she exults. "The gift is that I'm here...
...generation of gene-based treatments. She was 47 years old when she discovered a large lump in her breast. Tests showed that the malignancy had spread to her lymph nodes. Bradfield got the works: a double mastectomy and six months of chemotherapy, followed by radiation and then more chemo. It bought her 18 months of symptom-free life. Then one hot August night, she recalls, "I went to rub my neck, and there was a tumor about the size of a marshmallow." Bradfield was already depressed--her daughter had just died in a car accident--and she never wanted...
...antibody is not a panacea. It didn't work as well for Bradfield's fellow guinea pigs in the initial study. But results of a just completed trial with 470 women do show it to be a significant improvement over chemo alone for women with this awful form of breast cancer. The details of the study will be revealed by Slamon this Sunday at a meeting in Los Angeles of the American Society of Clinical Oncology. Manufactured by Genentech under the name Herceptin, the drug is on a fast track for approval by the FDA, perhaps before year...