Word: blood-vessel
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Once the immediate onslaught of pollution is gone, blood pressure drops back down. But the damaging effects persist. Particulates can lodge deep in the lungs, where they activate another process - inflammation, which kicks in over the 24 hours after exposure. The inflammatory response can stiffen blood vessels and cause longer-term damage to blood-vessel flexibility and their ability to absorb changes in blood flow from the heart. Weakened blood vessels can increase the risk of heart disease or stroke...
...that doesn't mean that every urban resident is at higher risk of heart disease. For most healthy people, the exposure to city air and transient changes in blood pressure isn't dangerous. But, says Brook, "it's plausible that if someone has underlying hypertension or coronary disease, then these changes in blood pressure and blood-vessel function might be exaggerated and might even trigger a heart attack. The levels at which we encounter these particles today is still dangerous to people who are unhealthy and at high risk." (See pictures of the effects of global warming...
Mention Dr. Judah Folkman's name to colleagues and patients and only the grandest descriptors come to their lips - words like "giant in his field," "visionary," "genius," and "ahead of his time." Credited with revolutionizing cancer treatment with the theory that preventing angiogenesis, or new blood-vessel growth, would starve tumors, the director of vascular biology at Children's Hospital and professor of pediatric surgery at Harvard Medical School died on Monday in Denver...
...good news, then, that Lucentis will likely get its FDA stamp of approval this week. Until now no approved treatment has improved sight in patients with AMD so well. Although Lucentis can't repair the irreversible retina damage that occurs when AMD has gone untreated, it prevents the blood-vessel leakage in the back of the eye that causes damage in the first place, leaving patients with distorted, wavy vision, and eventually a gap in the center of their vision. Up to 40% (depending on the dosage) of those in Lucentis trials improved their eyesight by at least three lines...
...have a repair shop like the Widener Hospital on hand. As would any doctor, one of the first things surgeon Dean Richardson did when Barbaro arrived was feel his patient's pulse--in several spots along the injured leg. Weak pulses or a cold foot would have meant that blood-vessel injury had occurred and the limb was lost. "He had good, strong pulses, and his foot was warm," says Richardson. "I was thrilled...