Word: alpha
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Dates: during 2000-2000
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...Brock, to help him get a good lead b Naomi Wolf, to transform him into an alpha male c Naomi Judd, just to keep her close d Don Cornelius, to help him get funky...
...first place to look for causes and treatments of Parkinson’s disease is in the brains of patients themselves. As the illness worsens, brain tissue becomes clogged with a protein muck that includes a substance called alpha-synuclein. No one knows exactly what alpha-synuclein does, but it’s believed to play a role in the smooth transmission of nerve signals. When the substance clumps, it can’t do the work it was designed to do, leading to neuron damage, loss of the neurotransmitter dopamine, and eventually to the familiar shakiness of such well-known Parkinson...
...hunt for a Parkinson’s cure got a boost in 1997, when researchers discovered a tiny population of patients who have a mutant gene that codes for alpha-synuclein. This might seem like open-and-shut evidence that the cause of the illness had been found, except that the vast majority of Parkinson’s patients, whose brains also grow gummed up, do not carry the mutation. Still, scientists are convinced that the bad gene is a powerful clue. "There appear to be more clumps in the brains of people with the mutant gene," says Zigmond. "Learning...
...also been getting a lot of attention. In 1998, Japanese researchers were studying a young patient with early-onset Parkinson’s and found a recessive gene that appeared to be associated with the disease. Though relatively rare, the parkin gene is much more common than the defective alpha-synuclein gene, and in places like China, with high rates of early-onset Parkinson’s, it may play a role in up to 20% of cases. Just last October, researchers at Duke University went a step further, discovering a previously unseen mutation on the parkin gene that appears to link...
...retrospect, was Ginger Spice's behavior inevitable? Do you think we ought to admit Red China to the United Nations? Did Oswald act alone? Why do you think Nixon didn't burn the tapes? Was Ronald Reagan a moron or a visionary? Do earth tones really signify the Alpha male? Why, exactly? Did Roosevelt know in advance about Pearl Harbor? You think those Sacco and Vanzetti guys got what they deserved? Did John F. Kennedy in the White House take his orders directly from the Pope of Rome? Would you say that Bill Clinton's roadless lands initiative unwisely ignores...