Word: stilbestrol
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...room and spent the night. The next morning he woke up very hung over, and she woke up possibly pregnant. Rather nonchalantly, but slightly nervously, she went to the Health Services and received the Morning After pill. For five days she took 50 grams of the artificial estrogen diethyl stilbestrol (DES) a day, was very nauseated, and felt ill the whole time. Yet, at the end of five days, she knew she wasn't pregnant. What she didn't know is that she was also very lucky. DES is a dangerous drug, which should not be sanctioned...
Beginning in 1946, pregnant women with histories of spontaneous abortions were frequently treated with diethylstilbestrol, an artificial hormone. No one knows the number of miscarriages prevented by stilbestrol among the many thousands of women who took it; by 1960, questions about the estrogen compound's efficacy had induced most doctors to avoid it in treating pregnant women. But there is no doubt that in at least a handful of cases, daughters of women so treated have fallen victim to vaginal cancer. The mothers' use of stilbestrol is suspected of planting a hormonal time bomb that can be deadly...
...patients had used contraceptive pills. Nor were their mothers' experiences with breastfeeding, exposure to X rays or smoking habits any different from the average. But seven of the eight patients' mothers had one thing in common: they had been considered vulnerable to miscarriage and had been given stilbestrol...
Unknown Mechanism. The Boston investigators do not claim to have proved that stilbestrol treatment was the cause of the cancers. But the evidence is so strong that Hollis S. Ingraham, New York State's commissioner of health, has sent a letter to 37,500 doctors warning them that synthetic estrogenic hormones should not be prescribed during pregnancy. He added that young women with irregular vaginal bleeding (usually attributed to ovulation failure) should be carefully checked for precancerous signs. Ingraham has also suggested to the U.S. Food and Drug Administration that it forbid outright the prescribing of stilbestrol during pregnancy...
POULTRY SALES are down as much as 75% in some areas as a result of FDA's program to withdraw capons injected with stilbestrol, a suspected cancer-producing hormone, from the market. The American Poultry and Hatchery Federation complained that the announcement caused many consumers to stop buying all chickens...