Word: progestin
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Dates: during 1990-1999
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...entirely reliable, and aesthetically satisfactory to husband and wife." Within 10 years, however, Pincus and his colleagues delivered, inventing the drug that sparked the sexual revolution. Introduced in the U.S. in 1960, the birth control pill, known simply as the Pill, was an ovulation-suppressing mix of estrogen and progestin that was 99% effective...
Drugs commonly used to break up clots and stabilize erratic heartbeats are less effective in women than in men. Hormone-replacement therapy-estrogen and progestin-has been shown to help. A U.S.-government study is currently under way that aims to clarify how estrogen works on the heart, brain and breast...
...cancer of the uterus, ovaries and cervix over the past five decades. Pap smears that detect abnormal cells in the cervix before they become malignant have contributed to a 75% drop in cervical cancer since the 1950s. Wider use of birth control pills and hormonereplacement therapy (with estrogen and progestin) have decreased the risk of ovarian and uterine cancers. Recent research also suggests that in some cases, a low-fat diet can cut the risk of cervical cancer even further...
Appropriate treatment is the big question. Estrogen replacement to stem the loss can increase the risk of breast cancer and, unless progestin is added in, endometrial cancer. A new medication, raloxifene, appears to stabilize bone loss while reducing the risk of breast cancer. Unlike traditional hormone-replacement therapy, however, raloxifene doesn't ease other menopausal symptoms, like hot flashes...
HORMONES OF A DILEMMA Adding progestin to estrogen-replacement therapy may weaken estrogen's healthy effect on the heart. But estrogen alone may raise the risk of uterine cancer...