Word: influenza
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Dates: during 1960-1969
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Died. Dr. Thomas Francis Jr., 69, pioneering American virologist and head of the epidemiology department at the University of Michigan; following abdominal surgery; in Ann Arbor, Mich. In 1934 Francis made medical history by isolating the classic A strain of influenza; he identified the virulent B strain in 1940, and by 1944 he had conquered both with a vaccine so dependable that it was used to inoculate the entire U.S. Army two years later. But his greatest success came in 1954, when he supervised (he unprecedented field trials (covering 1,800,000 children in 44 states at an expense...
...cancer of the blood," a fatal disease of the blood-forming organs. At about the same time, a 22-year-old Australian suffering from an obsessive-compulsive neurosis was treated with LSD injections for two months. A year later, suffering from fatigue, pallor, bleeding gums, rashes and an "influenza-like illness," he too was found to be a victim of acute leukemia...
...yesterday, though weakened by a mysterious influenza virus, it attacked the regatta when it needed to, leaving a strong Scottish Argonaut eight three seconds behind in the opening round of the Thames Challenge...
...drugs are recognized as highly effective against specific viral diseases: idoxuridine (IUDR) for corneal infections caused by the fever-blister virus, and methisazone against smallpox. What exercised the virologists most last week was a third chemical, amantadine, an anti-influenza drug that the Food and Drug Administration has licensed, but under strict controls. Trade-named Sym-metrel by E. I. du Pont de Nemours & Co., amantadine does not cure a fullblown case of flu. But it may prevent infection if taken before exposure, and mitigate the illness if taken early enough afterward. The trouble with amantadine is that...
Amantadine's effectiveness seems to be confined to the Asian A-2 strains of influenza virus. Last winter the U.S. Public Health Service, troubled by the drug's side effects, refused to approve its use against the newly emerging Hong Kong strain of A2. The stated reason was that its value had not been proved-though virologists complained at the Manhattan meeting that this was a disingenuous quibble. It could have been predicted, they said, that amantadine would prove as effective against the Hong Kong strain as it was against other...