Word: suspects
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That's why Herskowitz and his colleagues have launched a project to unravel exactly what--at the genetic level--makes some people benefit from drugs and others not. They suspect that one major factor is a class of proteins called membrane transporters. These proteins act as molecular gatekeepers, deciding which foreign substances in the bloodstream will be taken into and which rejected by individual cells. If, for example, people lack the gene for an inactivating enzyme, says Herskowitz, "a standard dose of a drug will be more potent. If they have an extra copy of the gene, a standard dose...
...pleased to find that a diet rich in fruits and veggies reduced the risk--at least in women--of the No. 1 cancer killer in the U.S. Apples, pears, cauliflower and grapefruit were particularly active against the incidence of lung cancer for reasons that are still unclear (although scientists suspect carotenoids may be powerful anticarcinogens). But the bottom line is that no quantity of cabbages and citrus fruit can outweigh the benefits of not smoking...
...understand the future of drugs used for anything other than doctor-approved healing. That market can be divided into three groups: the partyers, who just want to have fun (and who sometimes become addicts); the shrinks and shamans, who believe drugs can expand your consciousness; and the scientists, who suspect that illegal drugs--or their chemical cousins--may have marketable legal uses. These groups are distinct but tightly linked: scientific research leads to new drugs, which shamans discover and use in their quests, which often turn out to be as much fun as spiritual. The use of drugs in party...
Gentlemen: I must confess serious doubts about the efficacy—or even the integrity—of the “classic” exam period editorial, “Beating the System,” you reprinted recently. I almost suspect this so-called “Donald Carswell ’50” of being rather one of Us—the Bad Guys—than one of you. If your readers have been following Mr. Carswell’s advice for the last 11 years, then your readers have been going down the tubes...
...founders were more than a little ambivalent about royalty. A few of them even wanted Washington to be "President-for-life" (I believe that's called being king) and there was discussion of calling him Your Mightiness and Your Highness. (I suspect Bill Clinton might have enjoyed those titles.) It was also proposed that Washington wear a golden suit for his inauguration. Instead, Washington chose for himself the very down-to-earth American moniker of Mr. President and wore a plain brown suit with American eagles on the buttons...