Word: stemness
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According to David T. Scadden, co-director of the Harvard Stem Cell Institute (HSCI) and director of the new MGH Center for Regenerative Medicine housing the NHLBI project, the grant money—spread over five years—will help provide supplies, infrastructure, and salaries for scientists and staff...
Harvard’s move towards researching therapeutic applications will begin with hematopoietic stem cells—adult stem cells that give rise to blood cells. Unlike human embryonic stem cells, which are less well understood and have been the subject of ongoing ethical and legal debates, adult stem cells have already proven to be an effective treatment option...
...Right now, the one setting in which stem cells are being used clinically is with blood stem cells, and so the first proof of principle studies will be with these stem cells,” said Scadden. “That science, which is now decades in progress, is still fairly limited. There are certain areas of it that continue to have promise in people with terminal diseases...
Scadden stressed that the therapeutic direction in which work with adult stem cells is now moving will help lay the groundwork for a similar transition with embryonic stem cells...
...lead time for [embryonic stem cell clinical therapies] happening will be years,” he said. “What we are doing is putting forth an infrastructure with an adult stem cell focus—but one that can be ultimately adapted to embryonic stem cell work...