Word: stemness
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Scientists from Harvard and Columbia announced Thursday the creation of the first patient-specific stem cell line from humans afflicted with a genetic disease, a key step in the push to create therapies for a wide variety of illnesses by replacing diseased tissue with tissue generated by stem cells...
...study's two principal authors said in a press conference Wednesday that such treatments remained years away and that the more immediate impact of the disease-specific stem cells will be the ability to study disease progression and test potential treatments in a lab setting...
...cell donors—82 and 89—gave the findings added significance, as some scientists had predicted using cells from older patients would complicate the creation of stem lines, according to Eggan...
...This opens the door to being able to make patient-specific, stem cell lines from diseases which affect people very late in life like Parkinson's disease or Alzheimer's disease," Eggan said...
Though the researchers originally planned to produce disease and patient-specific stem cells using the controversial practice of therapeutic cloning, which requires both a supply of human egg cells and the destruction embryos created to produce the stem cell lines, they opted instead to use a newer technique called "direct reprogramming," which was first unveiled late last year...