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In a sample of 3,131 cancer specimens of 26 cancer types, the group identified 158 regions of focal somatic copy number alterations (SCNAs) that were frequently altered across several cancer types. Somatic copy number alterations occur when there are abnormal numbers of chromosomes within a tumor’s...
Although the exact role of SCNAs is still unclear, the researchers found that a large number of SCNAs identified in individual cancer types are present over several cancers of different origin. The common SCNAs may act as important markers in the diagnosis and treatment of cancer, according to Rameen Beroukhim...
The promise of their findings has already prompted funding from the National Institutes of Health, the Doris Duke Charitable Foundation, the Sarah Thomas Monopoli Lung Cancer Research Fund, the Lucas Foundation, and several drug companies—most notably Novartis—in the hope of developing drugs that may...
But even if all these pieces fall into place, there's still no assurance that the Democrats can find the votes to pass the bill in any form - especially in the House. Speaker Nancy Pelosi has virtually no room to maneuver: since her chamber adopted its original measure in November...
It's not clear why the past several months have been worse than ever, but President Morales says that, regardless of the reason, dangerous times call for drastic measures. Drivers claim the measure is authoritarian, but Morales has tried to show that no one will receive favoritism. Last month, soon...