Word: salk
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Among the 1.000,000 children that the foundation hopes to vaccinate there would be (by recent U.S. averages) 700 cases of detectable polio this summer. Of these. 483 would, sooner or later, recover completely, 175 would have some permanent paralysis and 42 would die. The value of Dr. Salk's vaccine will be measured by the extent to which it cuts the number of paralytic cases...
...meet these objections, Dr. Salk has had a busy season of needlework. In little more than five weeks he has inoculated almost 5,000 children in. the Pittsburgh area. Some have had three shots, some two, some one, all with vaccine made in his own laboratory. Now Dr. Salk has begun a marathon vaccinating program. Switching to commercial vaccine, he will try to inoculate 2,500 children this week and finish their quota of shots in time for the foundation to begin mass trials in the South about April 12. By then, enough commercial vaccine will be ready...
Endemic & Epidemic. It is still too early to answer the question, "Is this the year of victory over polio?" But there is good reason to believe that the Salk vaccine, or one of several on which work is proceeding in other laboratories, will give effective protection against the disease. This assurance lies in the body of knowledge, already immense and now growing faster than ever, that scientists have accumulated about polio. Most of this knowledge has been gained in the last 15 years by researchers working with grants from the National Foundation. It has taken so long because polio...
Some critics object to Salk's use of the Mahoney-(Type I) strain of virus because if any live particles slipped through they could cause severe paralysis after injection into muscle. Dr. Salk answers that if no live particles can get through, it cannot matter what they might do. And he makes sure, by the most rigorous testing that he has been able to devise, that every virus particle is killed. ^ Dr. Salk has had no unfavorable reactions with his vaccine. On the evidence to date, there is no reason for parents to withhold permission for their children...
...This year's mass trials are the greatest gamble in medical history," says a polio researcher, who, admittedly, favors a live-virus vaccine. But the gamble is sure to pay off one way or another. If the Salk vaccine is effective for even one season, 1954 will be a year of signal victory against polio; if it is not, little will have 3een lost and much knowledge gained for a new attack...