Word: randy
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Obama had just come off the other side of a comedy controversy, after Bernie Mac went to an Obama event and told dirty jokes (a.k.a. what Bernie Mac does for a living). Comics Randi Rhodes and Penn Jillette took heat for nasty jokes about Hillary Clinton; John McCain, for joking about using U.S. cigarette exports as a weapon to kill Iranians. Partisans argued over whether Saturday Night Live was more unfair to Obama than Comedy Central was to Clinton. Across America, the body politic is busily making mountains out of droll hills...
...research, prodded along by advocacy groups like the National Fragile X Foundation and FRAXA, is yielding insights that have implications for understanding and treating autism--and perhaps a number of other conditions too. "Fragile X is leading the autism field in terms of new treatments," says pediatrician Randi Hagerman, medical director of the MIND Institute. "We know the gene, we know a lot about the biology, and we know how to fix it. That's pretty exciting...
...biology of the disease is different too. In fragile X, the key gene is silent; in FXTAS patients, it's too active. "The gene produces up to 10 times more message than normal," explains molecular biologist Paul Hagerman of the University of California at Davis, who together with wife Randi has received an NIH grant to study the disorder. Over time, messenger RNA--the substance that transcribes genes into proteins--accumulates in the nuclei of brain cells, eventually poisoning them...
While scientists work out the molecular pathways that may someday cure FXS and FXTAS, clinicians at more than a dozen centers around the country are devising ways to improve life for affected families. Children with FXS are referred to programs that offer language services, occupational therapy and special education. Randi Hagerman is a believer in drugs to treat anxiety and hyperactivity. For patients with FXTAS, she prescribes exercise and medications already used to treat Parkinson's and Alzheimer's disease...
...trading power play opportunities. Buesser’s go-ahead goal led Princeton to pull its goalie with 1:36 to play. Harvard fought off the six-man attack and was able to add an insurance empty-net goal with under a minute left in the game.It was sophomore Randi Griffin who put the puck in the empty net. Vaillancourt and Cahow recorded assists on the play. “When you get into a situation where the opposing team pulls their goaltender, you know it’s going to be stressful,” Cahow said...