Word: prontosil
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Least known are the medical uses of wetting agents, first revealed in 1935 by Germany's Gerhard Domagk, who was awarded but could not accept a Nobel Prize (1939) for his work with prontosil (forerunner of sulfanilamide). In 1939 Dr. Benjamin Frank Miller of the University of Chicago was looking for an agent which would carry germicides into every nook & cranny of the teeth. Paging through LIFE one day, he ran across a picture of American Cyanamid's famous ducks being scuttled with its "Aerosol" wetting agent. Miller tried the same product on teeth, found that it penetrated...
...friend of Dr. Ralph Robertson Mellon in Pittsburgh lay dying from blood poisoning caused by streptococcus. In despair, Dr. Mellon gave him a dose of prontosil (sulfanilamide), a German drug never before tried on human beings in the U. S. To his joy, the dying man made a rapid recovery. That was three years...
...prize was ticketed for Professor Gerhard Domagk of Germany, who first showed the efficacy of prontosil (forerunner of the miracle-drug sulfanilamide) in treating streptococcal infections. The Nobel committee thus serenely ignored Adolf Hitler's ban on Nobel Prizes for Germans, wrathfully decreed by the Führer after the 1935 Peace Prize was awarded to tuberculous Pacifist Carl von Ossietsky, whom the Nazis had under heel in a concentration camp. Last week Professor Domagk discreetly referred to his Government the question of what to do about his award, murmured: "Even if I don't receive the money...
Domack, who lives in Wuppertal, Germany, was awarded the prize for his discovery of Prontosil, an anti-bacterial preparation used in the treatment of various infectious diseases...
...patient stricken with deadly peritonitis. In desperation he fed her a German-made drug, never before used in the U. S. The patient rapidly recovered. Dr. Mellon then plunged into an intensive study of the action of this drug, a combination of benzene, a sulfur compound and naphthalene, called prontosil. He learned that: 1) one of its three ingredients, naphthalene, was medically worthless; 2) sulfanilamide, a cheaper U. S. product, composed of the other two ingredients, would do everything prontosil could do. Last fortnight, together with Dr. Paul Gross and Frank B. Cooper, Pittsburgh Institute of Pathology chemist. Dr. Mellon...