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...study were included in the data, then the results would suggest a 31% effectiveness rate, with 51 in the vaccine arm and 74 in the control group becoming infected with HIV. These are the results that were announced in September. But because this particular vaccine comprised two older vaccines that were given in six doses over a six-month period - in what is referred to as a prime and boost regimen, in which the early shots prime the immune system to fend off HIV and the follow-up shots boost the body's immunity - some volunteers became infected with...

Author: /time Magazine | Title: Behind the Rising Doubts About Hailed AIDS Vaccine | 10/13/2009 | See Source »

From the outset, the vaccine strategy used in the NIH and U.S. Army study - giving two older vaccines in succession - has been controversial. In previous trials, each vaccine had failed to provide any protection against HIV, and in September 2004 a group of adamant scientists wrote a letter to Science arguing that the National Institute of Allergy and Infectious Diseases should not to continue with the trial. "We seriously question whether it is sensible now to conduct a ... trial that, in our opinion, is no more likely to generate a meaningful level of protection against infection or disease," they wrote...

Author: /time Magazine | Title: Behind the Rising Doubts About Hailed AIDS Vaccine | 10/13/2009 | See Source »

...mind when you were writing this book? Someone in some review somewhere mentioned Diane Arbus' photo of those young twins, and that's an iconic image for me. I'm a huge admirer of Diane Arbus. And even though my twins don't look like that and they're older, there's something in the way those two girls look at the camera. With her work, there's always this quality of looking at people maybe you feel you shouldn't be looking...

Author: /time Magazine | Title: Audrey Niffenegger on Her Ghostly New Novel | 10/9/2009 | See Source »

...portion of their paychecks. So companies held on to their pension systems even as they added 401(k)s, which by law they had to make available to all employees. When the market took off in the 1980s, the rank and file clamored to get in. (Read why older workers are happier...

Author: /time Magazine | Title: Why It's Time to Retire the 401(k) | 10/9/2009 | See Source »

...Saving more, another common prescription for fixing the 401(k), has its downside too. That's because of another unpleasant quirk of the 401(k), which was mentioned earlier: the older you are, the riskier a 401(k) gets. That's because contributions make up a very big part of the account's growth in the early years. Later on, once the account has grown, it is much more sensitive to market drops...

Author: /time Magazine | Title: Why It's Time to Retire the 401(k) | 10/9/2009 | See Source »

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