Word: nucleic
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DIED. Sol Spiegelman, 68, pioneering microbiologist whose research on DNA and RNA, the nucleic acids that carry life's hereditary coding, helped lay the foundation for genetic engineering; in New York City. Spiegelman showed how RNA serves as a kind of blueprint whose coded genetic information orders up the production of substances, and also discovered key links between viruses and human cancer...
What proved most significant about Berg's experiment, and helped win the prize, were the steps that immediately preceded it. The virus he wanted to introduce into the bacterium was itself a hybrid. By ingenious use of enzymes that can cut, patch and join nucleic acids, he and his colleagues managed to splice DNA from a bacterial virus into SV40's genes, forming a single closed loop. That was the first time scientists had been able to link the genes of two distinctly different species, and thus created the prospect of producing entirely new life forms...
...area that was just breaking was genetic engineering or recombinant DNA. That year, at a session on nucleic acids, researchers first voiced what was to become a national concern over the technology's possible dangers in creating new life forms. Among the most pregnant research areas taken up at this year's Gordon conferences: the structure and function of "endogenous opiates," pain-killing chemicals produced by the body itself, and the new field of bioelectrochemistry that is beginning to draw attention with the recent discovery that electric currents sometimes help knit stubborn bone fractures...
Thursday, May 4: Chemistry Department Seminar: Dr. Karen Gennette on Benzo Pyrene Diol Epoxides as Intermediates in Nucleic Acid Binding In Zitro and In Vivo, Science Center...
Doctors have long suspected that viruses, submicroscopic packets of nucleic acids similar to the DNA found in chromosomes, play a role in human as well as animal cancers. Dr. Sol Spiegelman, director of the Institute of Cancer Research at New York Columbia-Presbyterian Medical Center and one of the world's leading cancer virologists, points out that virus-like particles can be found in just about every human cancer. But proving that these particles cause the cancers has been more difficult. The cases against several suspect viruses have had to be dismissed for lack of scientific proof. There...