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Upon meeting a virus, the macrophage, which moves about, amoeba-like, on long cellular extensions known as pseudopods (false feet), does more than just ingest the intruder. It has another, even more important function. On its surface, like virtually all body cells, the macrophage carries MHC (for major histocompatibility complex) molecules, protein badges that enable other immune cells to recognize the macrophage as friend, or self, and not attack it. After digesting the virus, the macrophage proudly displays strips of protein from the virus in the grooves of some of its MHC molecules. Once a bit of protein -- which...

Author: /time Magazine | Title: Medicine: Stop That Germ! | 5/23/1988 | See Source »

...xenophobic zeal to destroy anything that is foreign to the body. Once the alien threat has been identified, agents known as helper T cells unleash the powerful immune response that attacks grafted tissue. During the 1970s, physicians found that they could minimize this reaction by more closely matching the MHC proteins, or immunological "dog tags," of a donor with those of the recipient. Even so, they could not completely eliminate the rejection response. To make matters worse, the only drugs available to weaken it shut down the defensive system completely, leaving patients vulnerable to viruses, bacteria or tumors. The triple...

Author: /time Magazine | Title: Medicine: How A Miracle Drug Disarms The Body's Defenses | 5/23/1988 | See Source »

Partial Federal funding is available for projects on the site, according to Mary Herbert of the Massachusetts Historical Commission(MHC). But the University has no immediate plans to apply for a grant, Donald C. Moulton, assistant vice president for Community Affairs, said yesterday...

Author: NO WRITER ATTRIBUTED | Title: Commission Names Old Yard New National Historical Site | 3/7/1973 | See Source »

...nominating the Old Yard to the National Park Service in May 1972, the MHC described the site as "a large three-shaded, roughly rectangular open space and smaller peripheral spaces to the west and south...

Author: NO WRITER ATTRIBUTED | Title: Commission Names Old Yard New National Historical Site | 3/7/1973 | See Source »

...that they needed more that just good intentions to do an effective jobs. They needed training and supervision. They had to become familiar with the critical problems in their fields and to develop tactics to deal with these concerns. In 1965, PBH committees such as the Mental Health Committee (MHC) began to use professional consultants to help them meet their needs. Several committees including the Cambridge Education Program and the Easy Reader Program, have since set up non-credit seminars and workshops to prepare students for volunteer work...

Author: By Benjamin Sendor, | Title: PBH: Learning to Save Its Own Problem | 11/10/1972 | See Source »

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