Word: mcgrath
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...Piano" begins, Ada McGrath (Oscar winner Holly Hunter) has become the mail-order bride of Alistair Stewart (Sam Neill), a farmer in the remote bush of nineteenth century New Zealand whom she has never met. Together with her nine-year-old daughter Flora (Academy Award winner Anna Paquin) and her piano, Ada makes the long voyage by sea from Scotland to New Zealand. When Stuart arrives to meet her, he refuses to transport her piano to their house, leaving it on the beach...
...shots or at most single games. Martina can no longer play a Martina match. The woman who once won 54 straight matches, lost one, then won 74 more, now keeps losing to players who have no business beating her. Last week in the warmup at Eastbourne it was Meredith McGrath of Michigan. Each defeat makes her less fearsome to the next journeywoman, often young enough to be her daughter...
...Francisco study, Dr. Michael McGrath and Dr. Bruce Shiramizu examined tissue from more than two dozen AIDS patients who suffered from lymphoma. In the majority of cases, they found what any AIDS researcher would expect. After infecting the lymph system, HIV uses its genetic material, RNA, as a template to produce viral DNA, which randomly incorporates itself into the cell's DNA. But in a few cases, the viral strands zeroed in on a particular stretch of cell DNA. When the investigators looked more closely, they discovered what is known as an oncogene nearby. Responsible for normal growth during development...
Like detectives who determine how a fire broke out by studying the way in which the house burned down, the researchers surmised that HIV had somehow switched on the dormant oncogene, causing the cell to divide repeatedly. "It surprised us at first," McGrath recalls. "We thought it was coincidence, but then it happened three more times and we knew we were on to something." The new cancer cells released yet more virus, which activated oncogenes in other cells, starting a deadly chain reaction...
...research suggests a possible strategy for treating lymphoma in these patients: attack HIV with antiviral drugs like interferon. "We don't know whether turning off HIV will turn off the cancer gene as well," McGrath admits. "But it's an approach we are eager to pursue...