Word: malariae
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...billions of dollars from the Gateses, no matter how leveraged, will not be nearly enough to reverse the slip-sliding decline in health in poor countries. There is an equally great risk that they will waste billions of dollars trying. To hedge their bets, they invest not in one malaria treatment, for example, but in many. And they try to stay flexible. After they were criticized for investing too heavily in new inventions, they put more money into distributing fixes that already exist. They also don't scare easily: when it was discovered that one kind of spermicide actually increased...
...increase the amount of time he devotes to the foundation. While it spends only 5% of its endowment a year (the minimum required under the tax code), Stonesifer says she would be happy to "blow past" that level for the right cause--like a vaccine for HIV or malaria...
...What we’re really trying to do is to capture [protein] information and leverage it to understand the biological system,” Quackenbush said. “The kinds of techniques that we’re talking about have broad applications, from looking at malaria to seeing how plants grow. We want to understand protein function and, more importantly, dysfunction in the context of diseases...
Keasling, 41, has spent the past 13 years at the University of California, Berkeley, working out how to trick E. coli microbes into churning out synthetic and beneficial versions of plant products. He was particularly interested in molecules known as terpenoids, like artemisinin, which treats malaria; taxol, an anticancer drug; and prostratin, a potential anti-HIV compound...
Artemisinin is critical to fighting malaria, a deadly global problem that kills up to 3 million people annually. The compound is found in wormwood plants that grow in Southeast Asia but costs $2.40 a dose. In developing countries, that might as well...