Word: liverence
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...anti-cancer drug, usually Methotrexate. The clock motor and pump are so delicate that they are capable of spreading this supply over a week, delivering it via a plastic tube pushed through a small incision into an artery or vein. Patients with cancers of the head, neck and liver have already been helped by home treatment with the Lahey device...
Precise Timing. The latest liver surgery in Denver involved the deathwatch and precise timing that are a common feature of homotransplants. Housewife Jeanine Goodfellow, 29, of Arvada, arrived at the University of Colorado Medical Center in September with cancer of the liver so advanced that her only real hope of life lay in taking the long chance of becoming the first human being to survive with a transplanted liver...
Across the street at Denver's VA Hospital, a man was admitted for accidental gunshot wounds, and when it became clear that he could not survive, relatives gave permission for the use of his liver in a transplant. As the prospective donor's life ebbed, Surgeon Thomas E. Starzl opened Mrs. Goodfellow's abdomen to get her ready for a quick transplant. This operation took ten hours. Her liver was so enlarged by disease that instead of a normal 4 Ibs. it weighed closer to 20 Ibs. Dr. Starzl left his patient anesthetized, with her liver "just...
Within minutes after the donor died, Ralph Huntley, a mechanical engineer who has switched to biophysics, began cooling the body "from the inside out" by perfusing it with chilled saline solution. He kept this up while Surgeon Thomas Marchioro cut out the liver. Dr. Starzl cut out Mrs. Goodfellow's diseased liver at almost the same moment as its replacement arrived in a chilled, sterile container. Then Dr. Starzl stitched the newly arrived liver in, connecting its blood vessels to their counterparts in Mrs. Goodfellow's body. This part of the operation took 164 minutes...
...days, Mrs. Goodfellow was kept in sterile isolation: the danger of infection had increased enormously because Mrs. Goodfellow's defenses against it had been weakened by the immunosuppressive drugs, Imuran and prednisone, that the doctors had given her to increase the likelihood that the liver graft would "take" instead of being rejected. Last week she was well enough to take a ride outside the hospital, but the crucial time, determining whether her system will accept or reject her grafted liver, is not likely to come until early in November...