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Scientists have suspected that FRMP exerts its braking action by attaching to receptors on the surface of brain cells, known as mGluR5 receptors (the Glu is for glutamate, a key signaling agent in the brain). They reasoned that it would be possible to correct the excesses of Fragile X by blocking these receptors, which act as accelerators of protein production. To test this idea, the researchers produced a special breed of mice that had the Fragile X trait but only half the normal number of mGluR5 receptors. The result, explains Bear: "We were able to correct the excesses [of Fragile...
...bench, the Harvard players were jumping up and down, celebrating every basket made. “I admire the energy on the bench,” coach Delaney-Smith said. “Group energy can help swing momentum.” As usual, the Crimson got key contributions from juniors Emily Tay and Niki Finelli, who added 12 and 11 points, respectively. The performance of the starters was supplemented by extremely solid bench play. Every available Harvard player got some game time, and 11 different scorers helped to ensure the blowout. The 24-point margin of victory was Harvard?...
...students he’s ever had are really impressed by him,” she said, adding that Brandt had played a key role in inspiring her to major in the History of Science. “I run into people from the freshman seminar still and they say, ‘Yeah, did you hear professor Brandt’s the new dean...
...bring parents along - to keep up in the classroom. All kids must wear their school uniforms and IDs - although, if they meet weekly attendance targets Hankerson sets, they can wear blue jeans on Fridays. That program has helped raise average student attendance this year to almost 94% - a key to raising class performance, say teachers...
...been spurred by its raised profile in Germany over the past year. The opening of its headquarters in Berlin in January put the organization back into the headlines, and it became the center of a national furor over the summer, when the Defense Ministry initially barred access to a key filming location for a movie about anti-Nazi hero Claus Schenk von Stauffenberg, because the title role was played by high-profile Scientologist Tom Cruise. (Germany later relented...