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...whether she should start taking aspirin daily. She had seen newspaper and TV reports claiming that the pills lower the risk of heart attacks, and she knew such risks increase dramatically for women after they stop menstruating. "My answer was dead silence," says the woman's physician, Dr. Elizabeth Karlin, who teaches at the University of Wisconsin medical school. A week later, after scouring the literature, Karlin came to what she called an "appalling" conclusion: the finding, trumpeted in some newspapers as a lifesaver for everyone, was based entirely upon research on men. "There were simply no data...

Author: /time Magazine | Title: Self & Society: Medicine A Perilous Gap | 11/8/1990 | See Source »

...Karlin had discovered an information gap that may be endangering millions of American women. A number of treatments now recommended for men and women -- from cholesterol-lowering drugs and diets to AIDS therapies and antidepressants -- have been studied almost exclusively in men. Little hard evidence exists about their efficacy or safety for women. The problem has begun to concern doctors, patients and now lawmakers. In June Congress's General Accounting Office released a report condemning the National Institutes of Health (NIH) for failing to promote studies that took adequate account of the differences between the sexes. The Congressional Caucus...

Author: /time Magazine | Title: Self & Society: Medicine A Perilous Gap | 11/8/1990 | See Source »

...trouble and expense of recruiting women research subjects, given that women make up half the population -- and half the taxpayers underwriting federal research. Concern for the fetus is often exaggerated, they say. "There is a tendency to think of women as walking wombs," says the University of Wisconsin's Karlin. Most female cardiac patients, she notes, are not planning to get pregnant...

Author: /time Magazine | Title: Self & Society: Medicine A Perilous Gap | 11/8/1990 | See Source »

DriverGuide, produced by Karlin & Collins, a Sunnyvale, Calif., firm, is the electronic equivalent of rolling down a window and asking for directions. The prototype unit looks like an automated-teller machine, but it issues information rather than cash. By punching buttons and choosing from a variety of screen menus, users specify where they want to go. Twenty seconds later, the machine spits out a printed sheet of driving instructions constructed from a data base that contains the location of every intersection and alleyway in the Bay area, including 3,400 turn restrictions and 4,800 traffic lights. Says Barry Karlin...

Author: /time Magazine | Title: Computers: Driving by the Glow of a Screen | 4/20/1987 | See Source »

...nation's urban areas, while K&C is programming Los Angeles, Miami and Atlanta. Both companies speak confidently of the day when onboard computers will act as mobile information systems, displaying everything from the latest traffic conditions to the location of the nearest hospital. Predicts Karlin: "Ten years from now, nobody will need to drive with a road map folding and flapping in the steering wheel...

Author: /time Magazine | Title: Computers: Driving by the Glow of a Screen | 4/20/1987 | See Source »

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